A Novel Leucyl-tRNA Synthetase Inhibitor, MRX-6038, Expresses Anti-Mycobacterium abscessus Activity In Vitro and In Vivo

Therapeutic options for Mycobacterium abscessus infections are extremely limited, and new drugs are needed. The anti-M. abscessus activity of MRX-6038, a new leucyl-tRNA synthetase inhibitor, was evaluated in vitro and in vivo. Antimicrobial susceptibility testing was performed on 12 nontuberculosis...

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Detalles Bibliográficos
Autores principales: Wu, Wenye, He, Siyuan, Li, Anqi, Guo, Qi, Tan, Zhili, Liu, Shicong, Wang, Xinghai, Zhang, Zhemin, Li, Bing, Chu, Haiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Susceptibility
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487484/
https://www.ncbi.nlm.nih.gov/pubmed/35969055
http://dx.doi.org/10.1128/aac.00601-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487484/
https://www.ncbi.nlm.nih.gov/pubmed/35969055
http://dx.doi.org/10.1128/aac.00601-22

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