Next-generation sequencing based detection of BRCA1 and BRCA2 large genomic rearrangements in Chinese cancer patients

BRCA1/2 mutation is a biomarker for guiding multiple solid tumor treatment. However, the prevalence of BRCA1/2 large genomic rearrangements (LGRs) in Chinese cancer patients has not been well revealed partially due to technical difficulties in LGR detection. This study utilized next-generation seque...

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Detalles Bibliográficos
Autores principales: Hua, Dingchao, Tian, Qiuhong, Wang, Xue, Bei, Ting, Cui, Lina, Zhang, Bei, Bao, Celimuge, Bai, Yuezong, Zhao, Xiaochen, Yuan, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487528/
https://www.ncbi.nlm.nih.gov/pubmed/36147908
http://dx.doi.org/10.3389/fonc.2022.898916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487528/
https://www.ncbi.nlm.nih.gov/pubmed/36147908
http://dx.doi.org/10.3389/fonc.2022.898916

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