Cargando…

Next-generation sequencing based detection of BRCA1 and BRCA2 large genomic rearrangements in Chinese cancer patients

BRCA1/2 mutation is a biomarker for guiding multiple solid tumor treatment. However, the prevalence of BRCA1/2 large genomic rearrangements (LGRs) in Chinese cancer patients has not been well revealed partially due to technical difficulties in LGR detection. This study utilized next-generation seque...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hua, Dingchao, Tian, Qiuhong, Wang, Xue, Bei, Ting, Cui, Lina, Zhang, Bei, Bao, Celimuge, Bai, Yuezong, Zhao, Xiaochen, Yuan, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487528/ https://www.ncbi.nlm.nih.gov/pubmed/36147908 http://dx.doi.org/10.3389/fonc.2022.898916

Ejemplares similares

Clinical significance of large rearrangements in BRCA1 and BRCA2
por: Judkins, Thaddeus, et al.
Publicado: (2012)

Metastatic Breast Cancer with BRCA Mutation Discovered By Next-Generation Sequencing Responding to Olaparib
por: Rizvi, Wajeeha, et al.
Publicado: (2017)

Molecular Trajectory of BRCA1 and BRCA2 Mutations
por: Hatano, Yuichiro, et al.
Publicado: (2020)

Analysis of BRCA Germline Mutations in Chinese Prostate Cancer Patients
por: Chen, Wei, et al.
Publicado: (2022)

Novel BRCA1 and BRCA2 genomic rearrangements in Southern Chinese breast/ovarian cancer patients
por: Kwong, Ava, et al.
Publicado: (2012)

Large Genomic Rearrangements of BRCA1 and BRCA2 among Patients Referred for Genetic Analysis in Galicia (NW Spain): Delimitation and Mechanism of Three Novel BRCA1 Rearrangements
por: Fachal, Laura, et al.
Publicado: (2014)

Large genomic rearrangements in BRCA1 and BRCA2 genes in breast and ovarian cancer families in Poland
por: Bielecka, Helena, et al.
Publicado: (2012)

Large genomic rearrangements in BRCA1 and BRCA2 genes in breast and ovarian cancer families in Poland
por: Bielecka, Helena, et al.
Publicado: (2012)

The contribution of large genomic rearrangements in BRCA1 and BRCA2 to South African familial breast cancer
por: van der Merwe, Nerina C., et al.
Publicado: (2020)

Identification of novel BRCA1 large genomic rearrangements by a computational algorithm of amplicon-based Next-Generation Sequencing data
por: Nicolussi, Arianna, et al.
Publicado: (2019)

Genomic rearrangements in BRCA1 and BRCA2: A literature review
por: Ewald, Ingrid Petroni, et al.
Publicado: (2009)

Globally Rare BRCA2 Variants With Founder Haplotypes in the South African Population: Implications for Point-of-Care Testing Based on a Single-Institution BRCA1/2 Next-Generation Sequencing Study
por: Oosthuizen, Jaco, et al.
Publicado: (2021)

Comparison of Targeted Next-Generation and Sanger Sequencing for the BRCA1 and BRCA2 Mutation Screening
por: Park, Joonhong, et al.
Publicado: (2016)

Landscape of germline BRCA1/BRCA2 variants in breast and ovarian cancer in Peru
por: Ferreyra, Yomali, et al.
Publicado: (2023)

Detection of BRCA1 and BRCA2 germline mutations in Japanese population using next-generation sequencing
por: Hirotsu, Yosuke, et al.
Publicado: (2015)

Identification of Eleven Novel BRCA Mutations in Tunisia: Impact on the Clinical Management of BRCA Related Cancers
por: Hamdi, Yosr, et al.
Publicado: (2021)

Case Report: A BRCA2 Mutation Identified Through Next-Generation Sequencing in a Birt–Hogg–Dubè Syndrome Family
por: Bandini, Erika, et al.
Publicado: (2022)

BRCA1 Versus BRCA2 and PARP Inhibitors Efficacy in Solid Tumors:A Meta-Analysis of Randomized Controlled Trials
por: Li, Shan, et al.
Publicado: (2021)

Beyond Breast and Ovarian Cancers: PARP Inhibitors for BRCA Mutation-Associated and BRCA-Like Solid Tumors
por: O’Sullivan, Ciara C., et al.
Publicado: (2014)

Analysis of BRCA1and BRCA2 large genomic rearrangements in Sri Lankan familial breast cancer patients and at risk individuals
por: De Silva, Sumadee, et al.
Publicado: (2014)

A multi-institutional study of the prevalence of BRCA1 and BRCA2 large genomic rearrangements in familial breast cancer patients
por: Seong, Moon-Woo, et al.
Publicado: (2014)

Development and Validation of a Next-Generation Sequencing Assay for BRCA1 and BRCA2 Variants for the Clinical Laboratory
por: Strom, Charles M., et al.
Publicado: (2015)

Design and validation of a next generation sequencing assay for hereditary BRCA1 and BRCA2 mutation testing
por: Kang, Hyunseok P., et al.
Publicado: (2016)

Performance evaluation of an amplicon‐based next‐generation sequencing panel for BRCA1 and BRCA2 variant detection
por: Park, Kuenyoul, et al.
Publicado: (2020)

BRCA1 and BRCA2 rearrangements in Brazilian individuals with Hereditary Breast and Ovarian Cancer Syndrome
por: Ewald, Ingrid Petroni, et al.
Publicado: (2016)

BRCA1 and BRCA2 Mutations Other Than the Founder Alleles Among Ashkenazi Jewish in the Population of Argentina
por: Solano, Angela R., et al.
Publicado: (2018)

Genomic Profiling Comparison of Germline BRCA and Non-BRCA Carriers Reveals CCNE1 Amplification as a Risk Factor for Non-BRCA Carriers in Patients With Triple-Negative Breast Cancer
por: Huang, Xin, et al.
Publicado: (2020)

The contribution of LARGE genomic rearrangements of BRCA1 and BRCA2 gene mutations in breast and ovarian cancer families in a clinical cohort
por: Sawyer, S, et al.
Publicado: (2012)

Recurrent BRCA1 Mutation, but no BRCA2 Mutation, in Vietnamese Patients with Ovarian Carcinoma Detected with Next Generation Sequencing
por: Vu, Hoang Anh, et al.
Publicado: (2020)

Next-generation sequencing of BRCA1 and BRCA2 genes in Moroccan prostate cancer patients with positive family history
por: Salmi, Fatiha, et al.
Publicado: (2021)

Screening for germline rearrangements in BRCA1 and BRCA2 in Norwegian families with breast or breast/ovarian cancer
por: Van Ghelue, M, et al.
Publicado: (2005)

Psychosocial impact of undergoing prostate cancer screening for men with BRCA1 or BRCA2 mutations
por: Bancroft, Elizabeth K., et al.
Publicado: (2018)

BRCA1 in the DNA damage response and at telomeres
por: Rosen, Eliot M.
Publicado: (2013)

Absence of rearrangements in the BRCA2 gene in human cancers
por: Chin, S-F, et al.
Publicado: (2001)

Surgical and Systemic Treatment of Hereditary Breast Cancer: A Mini-Review With a Focus on BRCA1 and BRCA2 Mutations
por: Pouptsis, Athanasios, et al.
Publicado: (2020)

Tumor Testing for Somatic and Germline BRCA1/BRCA2 Variants in Ovarian Cancer Patients in the Context of Strong Founder Effects
por: Peixoto, Ana, et al.
Publicado: (2020)

Prevalence and reclassification of BRCA1 and BRCA2 variants in a large, unselected Chinese Han breast cancer cohort
por: Liu, Yun, et al.
Publicado: (2021)

Next-generation sequencing of BRCA1 and BRCA2 genes for rapid detection of germline mutations in hereditary breast/ovarian cancer
por: Nicolussi, Arianna, et al.
Publicado: (2019)

Germline and Somatic BRCA1/2 Mutations in 172 Chinese Women With Epithelial Ovarian Cancer
por: You, Yan, et al.
Publicado: (2020)

Identification of large genomic rearrangement of BRCA1/2 in high risk patients in Korea
por: Kim, Do-Hoon, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_raaicd1392ds9cu213dk69ki48