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The Azithromycin Pro-Drug CSY5669 Boosts Bacterial Killing While Attenuating Lung Inflammation Associated with Pneumonia Caused by Methicillin-Resistant Staphylococcus aureus

Antibiotic resistance is a major problem, with methicillin-resistant Staphylococcus aureus (MRSA) being a prototypical example in surgical and community-acquired infections. S. aureus, like many pathogens, is immune evasive and able to multiply within host immune cells. Consequently, compounds that...

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Detalles Bibliográficos
Autores principales: Saris, Anno, Qin, Wanhai, van Linge, Christine C. A., Reijnders, Tom D. Y., Florquin, Sandrine, Burnet, Michael, Strass, Simon, de Vos, Alex F., van der Poll, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487537/
https://www.ncbi.nlm.nih.gov/pubmed/35972289
http://dx.doi.org/10.1128/aac.02298-21