Quantitative Pharmacodynamic Characterization of Resistance versus Heteroresistance of Colistin in E. coli Using a Semimechanistic Modeling of Killing Curves

Heteroresistance corresponds to the presence, in a bacterial isolate, of an initial small subpopulation of bacteria characterized by a significant reduction in their sensitivity to a given antibiotic. Mechanisms of heteroresistance versus resistance are poorly understood. The aim of this study was t...

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Detalles Bibliográficos
Autores principales: Mead, Andrew, Toutain, Pierre-Louis, Richez, Pascal, Pelligand, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487539/
https://www.ncbi.nlm.nih.gov/pubmed/36040146
http://dx.doi.org/10.1128/aac.00793-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487539/
https://www.ncbi.nlm.nih.gov/pubmed/36040146
http://dx.doi.org/10.1128/aac.00793-22

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