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Safety and Pharmacokinetics of Taniborbactam (VNRX-5133) with Cefepime in Subjects with Various Degrees of Renal Impairment

Taniborbactam, an investigational β-lactamase inhibitor that is active against both serine- and metallo-β-lactamases, is being developed in combination with cefepime to treat serious infections caused by multidrug-resistant Gram-negative bacteria. Anticipating the use of cefepime-taniborbactam in pa...

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Detalles Bibliográficos
Autores principales: Dowell, James A., Marbury, Thomas C., Smith, William B., Henkel, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487543/
https://www.ncbi.nlm.nih.gov/pubmed/35920662
http://dx.doi.org/10.1128/aac.00253-22