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Evolution of higher mesenchymal CD44 expression in the human lineage: A gene linked to cancer malignancy

CD44 is an extracellular matrix receptor implicated in cancer progression. CD44 increases the invasibility of skin (SF) and endometrial stromal fibroblasts (ESF) by cancer and trophoblast cells. We reasoned that the evolution of CD44 expression can affect both, the fetal–maternal interaction through...

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Detalles Bibliográficos
Autores principales: Ma, Xinghong, Dighe, Anasuya, Maziarz, Jamie, Neumann, Edwin, Erkenbrack, Eric, Hei, Yuan-Yuan, Liu, Yansheng, Suhail, Yasir, Pak, Irene, Levchenko, Andre, Wagner, Günter P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487634/
https://www.ncbi.nlm.nih.gov/pubmed/36148042
http://dx.doi.org/10.1093/emph/eoac036