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CD4(+) T-cell DNA methylation changes during pregnancy significantly correlate with disease-associated methylation changes in autoimmune diseases

Epigenetics may play a central, yet unexplored, role in the profound changes that the maternal immune system undergoes during pregnancy and could be involved in the pregnancy-induced modulation of several autoimmune diseases. We investigated changes in the methylome in isolated circulating CD4(+) T-...

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Detalles Bibliográficos
Autores principales: Badam, Tejaswi V., Hellberg, Sandra, Mehta, Ratnesh B., Lechner-Scott, Jeannette, Lea, Rodney A., Tost, Jorg, Mariette, Xavier, Svensson-Arvelund, Judit, Nestor, Colm E., Benson, Mikael, Berg, Göran, Jenmalm, Maria C., Gustafsson, Mika, Ernerudh, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487751/
https://www.ncbi.nlm.nih.gov/pubmed/34605719
http://dx.doi.org/10.1080/15592294.2021.1982510