Repurposing epigenetic inhibitors to target the Clostridioides difficile-specific DNA adenine methyltransferase and sporulation regulator CamA

Epigenetically targeted therapeutic development, particularly for SAM-dependent methylations of DNA, mRNA and histones has been proceeding rapidly for cancer treatments over the past few years. However, this approach has barely begun to be exploited for developing new antibiotics, despite an overwhe...

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Detalles Bibliográficos
Autores principales: Zhou, Jujun, Horton, John R., Yu, Dan, Ren, Ren, Blumenthal, Robert M., Zhang, Xing, Cheng, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487755/
https://www.ncbi.nlm.nih.gov/pubmed/34523387
http://dx.doi.org/10.1080/15592294.2021.1976910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487755/
https://www.ncbi.nlm.nih.gov/pubmed/34523387
http://dx.doi.org/10.1080/15592294.2021.1976910

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