Inhibitory prodrug mechanism for cysteine cathepsin-targeted self-controlled drug release

Tumour-associated macrophages (TAMs) support tumour development and have emerged as important regulators of therapeutic response to cytostatic agents. To target TAMs, we have developed a novel drug delivery approach which induces drug release as it inhibits cysteine cathepsin activity. This inhibito...

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Detalles Bibliográficos
Autores principales: van Dalen, Floris J., Verdoes, Martijn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487864/
https://www.ncbi.nlm.nih.gov/pubmed/36120947
http://dx.doi.org/10.1080/14756366.2022.2122961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487864/
https://www.ncbi.nlm.nih.gov/pubmed/36120947
http://dx.doi.org/10.1080/14756366.2022.2122961

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