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Inhibitory prodrug mechanism for cysteine cathepsin-targeted self-controlled drug release
Tumour-associated macrophages (TAMs) support tumour development and have emerged as important regulators of therapeutic response to cytostatic agents. To target TAMs, we have developed a novel drug delivery approach which induces drug release as it inhibits cysteine cathepsin activity. This inhibito...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487864/ https://www.ncbi.nlm.nih.gov/pubmed/36120947 http://dx.doi.org/10.1080/14756366.2022.2122961 |