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Acteoside and ursolic acid synergistically protects H(2)O(2)-induced neurotrosis by regulation of AKT/mTOR signalling: from network pharmacology to experimental validation

CONTEXT: Ursolic acid (UA) and acteoside (ATS) are important active components that have been used to treat Alzheimer’s disease (AD) because of their neuroprotective effects, but the exact mechanism is still unclear. OBJECTIVE: Network pharmacology was used to explore the mechanism of UA + ATS in tr...

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Detalles Bibliográficos
Autores principales: Qu, Yan-Jie, Ding, Min-Rui, Gu, Chao, Zhang, Li-Min, Zhen, Rong-Rong, Chen, Jin-Fang, Hu, Bing, An, Hong-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487927/
https://www.ncbi.nlm.nih.gov/pubmed/36102631
http://dx.doi.org/10.1080/13880209.2022.2098344