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Hepatocyte-targeting and tumor microenvironment-responsive liposomes for enhanced anti-hepatocarcinoma efficacy

To increase the antitumor drug concentration in the liver tumor site and improve the therapeutic effects, a functionalized liposome (PPP-LIP) with tumor targetability and enhanced internalization after matrix metalloproteinase-2 (MMP2)-triggered cell-penetrating peptide (TATp) exposure was modified...

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Detalles Bibliográficos
Autores principales: Cheng, Dongliang, Wen, Zhiwei, Chen, Hui, Lin, Shiyuan, Zhang, Wei, Tang, Xin, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487930/
https://www.ncbi.nlm.nih.gov/pubmed/36104946
http://dx.doi.org/10.1080/10717544.2022.2122635