Cargando…
Synthesis and antitumor activity of litseaone B analogues as tubulin polymerisation inhibitors
A series of litseaone B analogues 4a∼4p were synthesised and antitumor activities of all compounds were screened. These compounds were designed by introducing different substituents on the B ring. Among these synthesised compounds, it was proved that 4k showed excellent activity against A549, HepG2,...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487931/ https://www.ncbi.nlm.nih.gov/pubmed/36100238 http://dx.doi.org/10.1080/14756366.2022.2122962 |