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Synthesis and antitumor activity of litseaone B analogues as tubulin polymerisation inhibitors

A series of litseaone B analogues 4a∼4p were synthesised and antitumor activities of all compounds were screened. These compounds were designed by introducing different substituents on the B ring. Among these synthesised compounds, it was proved that 4k showed excellent activity against A549, HepG2,...

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Detalles Bibliográficos
Autores principales: Yang, Wei, Peng, Huining, Huang, Yong, Peng, Zhiyun, Wang, Guangcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487931/
https://www.ncbi.nlm.nih.gov/pubmed/36100238
http://dx.doi.org/10.1080/14756366.2022.2122962

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