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Polyphyllin II induced apoptosis of NSCLC cells by inhibiting autophagy through the mTOR pathway

CONTEXT: Polyphyllin II (PPII) is a steroidal saponin isolated from Rhizoma Paridis. It exhibits significant antitumor activity such as anti-proliferation and pro-apoptosis in lung cancer. OBJECTIVE: To explore whether PPII induce autophagy and the relationship between autophagy and apoptosis in non...

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Detalles Bibliográficos
Autores principales: Jiao, Yuhan, Xin, Ming, Xu, Juanjuan, Xiang, Xindong, Li, Xuan, Jiang, Jingjing, Jia, Xiuqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9487979/
https://www.ncbi.nlm.nih.gov/pubmed/36102594
http://dx.doi.org/10.1080/13880209.2022.2120021