A comparative study of tumour-on-chip models with patient-derived xenografts for predicting chemotherapy efficacy in colorectal cancer patients

Inter-patient and intra-tumour heterogeneity (ITH) have prompted the need for a more personalised approach to cancer therapy. Although patient-derived xenograft (PDX) models can generate drug response specific to patients, they are not sustainable in terms of cost and time and have limited scalabili...

Descripción completa

Detalles Bibliográficos
Autores principales: Ong, Louis Jun Ye, Chia, Shumei, Wong, Stephen Qi Rong, Zhang, Xiaoqian, Chua, Huiwen, Loo, Jia Min, Chua, Wei Yong, Chua, Clarinda, Tan, Emile, Hentze, Hannes, Tan, Iain Beehuat, DasGupta, Ramanuj, Toh, Yi-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488115/
https://www.ncbi.nlm.nih.gov/pubmed/36147524
http://dx.doi.org/10.3389/fbioe.2022.952726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488115/
https://www.ncbi.nlm.nih.gov/pubmed/36147524
http://dx.doi.org/10.3389/fbioe.2022.952726

Ejemplares similares