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COPD in individuals with the PiMZ alpha-1 antitrypsin genotype

Since the discovery of severe alpha-1 antitrypsin deficiency as a genetic risk factor for emphysema, there has been ongoing debate over whether individuals with intermediate deficiency with one protease inhibitor Z allele (PiMZ, or MZ) are at some risk for emphysema. This is important, because MZ in...

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Detalles Bibliográficos
Autores principales: Al Ashry, Haitham S., Strange, Charlie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488576/
https://www.ncbi.nlm.nih.gov/pubmed/29070580
http://dx.doi.org/10.1183/16000617.0068-2017