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Role of endothelial CXCR4 in the development of aortic valve stenosis

BACKGROUND: CXCL12/CXCR4 signaling is essential in cardiac development and repair, however, its contribution to aortic valve stenosis (AVS) remains unclear. In this study, we tested the role of endothelial CXCR4 on the development of AVS. MATERIALS AND METHODS: We generated CXCR4 endothelial cell-sp...

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Detalles Bibliográficos
Autores principales: Winnicki, Anna, Gadd, James, Ohanyan, Vahagn, Hernandez, Gilbert, Wang, Yang, Enrick, Molly, McKillen, Hannah, Kiedrowski, Matthew, Kundu, Dipan, Kegecik, Karlina, Penn, Marc, Chilian, William M., Yin, Liya, Dong, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488705/
https://www.ncbi.nlm.nih.gov/pubmed/36148060
http://dx.doi.org/10.3389/fcvm.2022.971321