Measuring the latent reservoir for HIV-1: Quantification bias in near full-length genome sequencing methods

Antiretroviral therapy (ART) effectively inhibits HIV-1 replication but is not curative due to the persistence of a latent viral reservoir in resting CD4(+) T cells. This reservoir is a major barrier to cure. Sequencing studies have revealed that the population of proviruses persisting in ART-treate...

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Detalles Bibliográficos
Autores principales: White, Jennifer A., Kufera, Joshua T., Bachmann, Niklas, Dai, Weiwei, Simonetti, Francesco R., Armstrong, Ciara, Lai, Jun, Beg, Subul, Siliciano, Janet D., Siliciano, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488763/
https://www.ncbi.nlm.nih.gov/pubmed/36074794
http://dx.doi.org/10.1371/journal.ppat.1010845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488763/
https://www.ncbi.nlm.nih.gov/pubmed/36074794
http://dx.doi.org/10.1371/journal.ppat.1010845

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