Hrq1/RECQL4 regulation is critical for preventing aberrant recombination during DNA intrastrand crosslink repair and is upregulated in breast cancer

Human RECQL4 is a member of the RecQ family of DNA helicases and functions during DNA replication and repair. RECQL4 mutations are associated with developmental defects and cancer. Although RECQL4 mutations lead to disease, RECQL4 overexpression is also observed in cancer, including breast and prost...

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Detalles Bibliográficos
Autores principales: Luong, Thong T., Li, Zheqi, Priedigkeit, Nolan, Parker, Phoebe S., Böhm, Stefanie, Rapchak, Kyle, Lee, Adrian V., Bernstein, Kara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488787/
https://www.ncbi.nlm.nih.gov/pubmed/36126066
http://dx.doi.org/10.1371/journal.pgen.1010122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488787/
https://www.ncbi.nlm.nih.gov/pubmed/36126066
http://dx.doi.org/10.1371/journal.pgen.1010122

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