Cargando…
Use of multitarget tyrosine kinase inhibitors to attenuate platelet-derived growth factor signalling in lung disease
Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) play a fundamental role in the embryonic development of the lung. Aberrant PDGF signalling has been documented convincingly in a large variety of pulmonary diseases, including idiopathic pulmonary arterial hypertension, lung cancer...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488848/ https://www.ncbi.nlm.nih.gov/pubmed/29070579 http://dx.doi.org/10.1183/16000617.0061-2017 |