Synthesis and biological evaluation of (+)-paeoveitol derivatives as novel antidepressants

The antidepressant activity of (+) and (−)-paeoveitol was first evaluated using the forced swimming test (FST), and (+)-paeoveitol showed potential antidepressant activity by decreasing immobility time of mice (by approximately 26.4%) in the FST at a dose of 20 mg/kg. To explore the structure-activi...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Tian-Ze, Huang, Xiao-Yan, Sun, Jin-Jin, Geng, Chang-An, Zhang, Xue-Mei, Chen, Ji-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488892/
https://www.ncbi.nlm.nih.gov/pubmed/36159033
http://dx.doi.org/10.1007/s00044-022-02973-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488892/
https://www.ncbi.nlm.nih.gov/pubmed/36159033
http://dx.doi.org/10.1007/s00044-022-02973-0

Ejemplares similares