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Synthesis and biological evaluation of (+)-paeoveitol derivatives as novel antidepressants
The antidepressant activity of (+) and (−)-paeoveitol was first evaluated using the forced swimming test (FST), and (+)-paeoveitol showed potential antidepressant activity by decreasing immobility time of mice (by approximately 26.4%) in the FST at a dose of 20 mg/kg. To explore the structure-activi...
Autores principales: | Li, Tian-Ze, Huang, Xiao-Yan, Sun, Jin-Jin, Geng, Chang-An, Zhang, Xue-Mei, Chen, Ji-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488892/ https://www.ncbi.nlm.nih.gov/pubmed/36159033 http://dx.doi.org/10.1007/s00044-022-02973-0 |
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