Hydroxamic Acid-Modified Peptide Library Provides Insights into the Molecular Basis for the Substrate Selectivity of HDAC Corepressor Complexes

[Image: see text] Targeting the lysine deacetylase activity of class I histone deacetylases (HDACs) is potentially beneficial for the treatment of several diseases including human immunodeficiency virus (HIV) infection, Alzheimer’s disease, and various cancers. It is therefore important to understan...

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Detalles Bibliográficos
Autores principales: Archibald, Lewis J., Brown, Edward A., Millard, Christopher J., Watson, Peter J., Robertson, Naomi S., Wang, Siyu, Schwabe, John W. R., Jamieson, Andrew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488896/
https://www.ncbi.nlm.nih.gov/pubmed/35973051
http://dx.doi.org/10.1021/acschembio.2c00510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488896/
https://www.ncbi.nlm.nih.gov/pubmed/35973051
http://dx.doi.org/10.1021/acschembio.2c00510

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