TLR2-induced CD8(+) T-cell deactivation shapes dendritic cell differentiation in the bone marrow during sepsis

Sepsis is associated with profound immune dysregulation that increases the risk for life-threatening secondary infections: Dendritic cells (DCs) undergo functional reprogramming due to yet unknown changes during differentiation in the bone marrow (BM). In parallel, lymphopenia and exhaustion of T ly...

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Detalles Bibliográficos
Autores principales: Antoni, Anne-Charlotte, Pylaeva, Ekaterina, Budeus, Bettina, Jablonska, Jadwiga, Klein-Hitpaß, Ludger, Dudda, Marcel, Flohé, Stefanie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488929/
https://www.ncbi.nlm.nih.gov/pubmed/36148245
http://dx.doi.org/10.3389/fimmu.2022.945409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9488929/
https://www.ncbi.nlm.nih.gov/pubmed/36148245
http://dx.doi.org/10.3389/fimmu.2022.945409

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