Isolated MLH1 Loss by Immunohistochemistry Because of Benign Germline MLH1 Polymorphisms

Mismatch repair (MMR) immunohistochemistry (IHC) is frequently used to inform prognosis, select (immuno-)therapy, and identify patients for heritable cancer syndrome testing. However, false-negative and false-positive MMR IHC interpretations have been described. MATERIALS AND METHODS: Following iden...

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Detalles Bibliográficos
Autores principales: Bosch, Dustin E., Yeh, Matthew M., Salipante, Stephen J., Jacobson, Angela, Cohen, Stacey A., Konnick, Eric Q., Paulson, Vera A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2022
Materias:
ORIGINAL REPORTS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489174/
https://www.ncbi.nlm.nih.gov/pubmed/36044719
http://dx.doi.org/10.1200/PO.22.00227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489174/
https://www.ncbi.nlm.nih.gov/pubmed/36044719
http://dx.doi.org/10.1200/PO.22.00227

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