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Isolated MLH1 Loss by Immunohistochemistry Because of Benign Germline MLH1 Polymorphisms
Mismatch repair (MMR) immunohistochemistry (IHC) is frequently used to inform prognosis, select (immuno-)therapy, and identify patients for heritable cancer syndrome testing. However, false-negative and false-positive MMR IHC interpretations have been described. MATERIALS AND METHODS: Following iden...
Autores principales: | Bosch, Dustin E., Yeh, Matthew M., Salipante, Stephen J., Jacobson, Angela, Cohen, Stacey A., Konnick, Eric Q., Paulson, Vera A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489174/ https://www.ncbi.nlm.nih.gov/pubmed/36044719 http://dx.doi.org/10.1200/PO.22.00227 |
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