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The cystic fibrosis lung microenvironment alters antibiotic activity: causes and effects

Chronic airway colonisation by Pseudomonas aeruginosa, a hallmark of cystic fibrosis (CF) lung disease, is associated with increased morbidity and mortality and despite aggressive antibiotic treatment, P. aeruginosa is able to persist in CF airways. In vitro antibiotic susceptibility assays are poor...

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Detalles Bibliográficos
Autores principales: Van den Bossche, Sara, De Broe, Emma, Coenye, Tom, Van Braeckel, Eva, Crabbé, Aurélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489179/
https://www.ncbi.nlm.nih.gov/pubmed/34526313
http://dx.doi.org/10.1183/16000617.0055-2021