Global chromatin mobility induced by a DSB is dictated by chromosomal conformation and defines the HR outcome

Repair of DNA double-strand breaks (DSBs) is crucial for genome integrity. A conserved response to DSBs is an increase in chromatin mobility that can be local, at the site of the DSB, or global, at undamaged regions of the genome. Here, we address the function of global chromatin mobility during hom...

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Detalles Bibliográficos
Autores principales: García Fernández, Fabiola, Almayrac, Etienne, Carré Simon, Ànnia, Batrin, Renaud, Khalil, Yasmine, Boissac, Michel, Fabre, Emmanuelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489209/
https://www.ncbi.nlm.nih.gov/pubmed/36125964
http://dx.doi.org/10.7554/eLife.78015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489209/
https://www.ncbi.nlm.nih.gov/pubmed/36125964
http://dx.doi.org/10.7554/eLife.78015

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