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DI-3-n-butylphthalide mitigates stress-induced cognitive deficits in mice through inhibition of NLRP3-Mediated neuroinflammation

Our previous study has demonstrated that chronic stress could cause cognitive deficits and tau pathology. However, the underlying mechanism and whether/how DI-3-n-Butylphthalide (NBP) ameliorates these effects are still unclear. Here, Wild-type mice were subjected to chronic unpredictable and mild s...

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Detalles Bibliográficos
Autores principales: Chen, Xiu, He, Juan-Ling, Liu, Xue-Ting, Zhao, Na, Geng, Fan, Zhu, Meng-Meng, Liu, Gong-Ping, Ren, Qing-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489537/
https://www.ncbi.nlm.nih.gov/pubmed/36160816
http://dx.doi.org/10.1016/j.ynstr.2022.100486