Human Endogenous Retrovirus K Envelope in Spinal Fluid of Amyotrophic Lateral Sclerosis Is Toxic

OBJECTIVE: Human endogenous retroviruses have been implicated in neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). Expression of human endogenous retrovirus K (HERV‐K) subtype HML‐2 envelope (Env) in human neuronal cultures and in transgenic mice results in neurotoxicity and...

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Detalles Bibliográficos
Autores principales: Steiner, Joseph P., Bachani, Muzna, Malik, Nasir, DeMarino, Catherine, Li, Wenxue, Sampson, Kevon, Lee, Myoung‐Hwa, Kowalak, Jeffery, Bhaskar, Manju, Doucet‐O'Hare, Tara, Garcia‐Montojo, Marta, Cowen, Maria, Smith, Bryan, Reoma, Lauren Bowen, Medina, Julie, Brunel, Joanna, Pierquin, Justine, Charvet, Benjamin, Perron, Hervé, Nath, Avindra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489628/
https://www.ncbi.nlm.nih.gov/pubmed/35801347
http://dx.doi.org/10.1002/ana.26452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489628/
https://www.ncbi.nlm.nih.gov/pubmed/35801347
http://dx.doi.org/10.1002/ana.26452

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