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Glucocorticoid receptor activation reduces food intake independent of hyperglycemia in zebrafish

Chronic cortisol exposure suppresses food intake in fish, but the central mechanism(s) involved in appetite regulation are unclear. Stress and the associated increase in cortisol levels increase hepatic gluconeogenesis, leading to hyperglycemia. As hyperglycemia causes a reduction in food intake, we...

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Detalles Bibliográficos
Autores principales: Nipu, Niepukolie, Antomagesh, Femilarani, Faught, Erin, Vijayan, Mathilakath M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489701/
https://www.ncbi.nlm.nih.gov/pubmed/36127383
http://dx.doi.org/10.1038/s41598-022-19572-z