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Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling
Adhesion G protein-coupled receptors (aGPCRs) are keys of many physiological events and attractive targets for various diseases. aGPCRs are also known to be capable of self-activation via an autoproteolysis process that removes the inhibitory GAIN domain on the extracellular side of receptor and rel...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489763/ https://www.ncbi.nlm.nih.gov/pubmed/36127364 http://dx.doi.org/10.1038/s41467-022-33173-4 |