Single-cell transcriptome reveals cellular hierarchies and guides p-EMT-targeted trial in skull base chordoma

Skull base chordoma (SBC) is a bone cancer with a high recurrence rate, high radioresistance rate, and poorly understood mechanism. Here, we profiled the transcriptomes of 90,691 single cells, revealed the SBC cellular hierarchies, and explored novel treatment targets. We identified a cluster of ste...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Qilin, Fei, Lijiang, Han, Rui, Huang, Ruofan, Wang, Yongfei, Chen, Hong, Yao, Boyuan, Qiao, Nidan, Wang, Zhe, Ma, Zengyi, Ye, Zhao, Zhang, Yichao, Wang, Weiwei, Wang, Ye, Kong, Lin, Shou, Xuefei, Cao, Xiaoyun, Zhou, Xiang, Shen, Ming, Cheng, Haixia, Yao, Zhenwei, Zhang, Chao, Guo, Guoji, Zhao, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489773/
https://www.ncbi.nlm.nih.gov/pubmed/36127333
http://dx.doi.org/10.1038/s41421-022-00459-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489773/
https://www.ncbi.nlm.nih.gov/pubmed/36127333
http://dx.doi.org/10.1038/s41421-022-00459-2

Ejemplares similares