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Single-cell transcriptome reveals cellular hierarchies and guides p-EMT-targeted trial in skull base chordoma
Skull base chordoma (SBC) is a bone cancer with a high recurrence rate, high radioresistance rate, and poorly understood mechanism. Here, we profiled the transcriptomes of 90,691 single cells, revealed the SBC cellular hierarchies, and explored novel treatment targets. We identified a cluster of ste...
Autores principales: | Zhang, Qilin, Fei, Lijiang, Han, Rui, Huang, Ruofan, Wang, Yongfei, Chen, Hong, Yao, Boyuan, Qiao, Nidan, Wang, Zhe, Ma, Zengyi, Ye, Zhao, Zhang, Yichao, Wang, Weiwei, Wang, Ye, Kong, Lin, Shou, Xuefei, Cao, Xiaoyun, Zhou, Xiang, Shen, Ming, Cheng, Haixia, Yao, Zhenwei, Zhang, Chao, Guo, Guoji, Zhao, Yao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489773/ https://www.ncbi.nlm.nih.gov/pubmed/36127333 http://dx.doi.org/10.1038/s41421-022-00459-2 |
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