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Diabetes downregulates the antimicrobial peptide psoriasin and increases E. coli burden in the urinary bladder
Diabetes is known to increase susceptibility to infections, partly due to impaired granulocyte function and changes in the innate immunity. Here, we investigate the effect of diabetes, and high glucose on the expression of the antimicrobial peptide, psoriasin and the putative consequences for E. col...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489794/ https://www.ncbi.nlm.nih.gov/pubmed/36127330 http://dx.doi.org/10.1038/s41467-022-32636-y |