Diabetes downregulates the antimicrobial peptide psoriasin and increases E. coli burden in the urinary bladder

Diabetes is known to increase susceptibility to infections, partly due to impaired granulocyte function and changes in the innate immunity. Here, we investigate the effect of diabetes, and high glucose on the expression of the antimicrobial peptide, psoriasin and the putative consequences for E. col...

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Detalles Bibliográficos
Autores principales: Mohanty, Soumitra, Kamolvit, Witchuda, Scheffschick, Andrea, Björklund, Anneli, Tovi, Jonas, Espinosa, Alexander, Brismar, Kerstin, Nyström, Thomas, Schröder, Jens M., Östenson, Claes-Göran, Aspenström, Pontus, Brauner, Hanna, Brauner, Annelie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489794/
https://www.ncbi.nlm.nih.gov/pubmed/36127330
http://dx.doi.org/10.1038/s41467-022-32636-y

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