Thin filament cardiomyopathies: A review of genetics, disease mechanisms, and emerging therapeutics

All muscle contraction occurs due to the cyclical interaction between sarcomeric thin and thick filament proteins within the myocyte. The thin filament consists of the proteins actin, tropomyosin, Troponin C, Troponin I, and Troponin T. Mutations in these proteins can result in various forms of card...

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Detalles Bibliográficos
Autores principales: Keyt, Lucas K., Duran, Jason M., Bui, Quan M., Chen, Chao, Miyamoto, Michael I., Silva Enciso, Jorge, Tardiff, Jil C., Adler, Eric D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489950/
https://www.ncbi.nlm.nih.gov/pubmed/36158814
http://dx.doi.org/10.3389/fcvm.2022.972301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9489950/
https://www.ncbi.nlm.nih.gov/pubmed/36158814
http://dx.doi.org/10.3389/fcvm.2022.972301

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