The role of structural dynamics in the thermal adaptation of hyperthermophilic enzymes

Proteins from hyperthermophilic organisms are evolutionary optimised to adopt functional structures and dynamics under conditions in which their mesophilic homologues are generally inactive or unfolded. Understanding the nature of such adaptation is of crucial interest to clarify the underlying mech...

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Detalles Bibliográficos
Autores principales: Fusco, Giuliana, Bemporad, Francesco, Chiti, Fabrizio, Dobson, Christopher M., De Simone, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490001/
https://www.ncbi.nlm.nih.gov/pubmed/36158582
http://dx.doi.org/10.3389/fmolb.2022.981312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490001/
https://www.ncbi.nlm.nih.gov/pubmed/36158582
http://dx.doi.org/10.3389/fmolb.2022.981312

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