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Sex difference in circulating PCSK9 and its clinical implications

Proprotein convertase subtilisin kexin type 9 (PCSK9) is a proprotein convertase that increases plasma low-density lipoprotein cholesterol (LDL-C) levels by triggering the degradation of LDL receptors (LDLRs). Beyond the regulation of circulating LDL-C, PCSK9 also has direct atherosclerotic effects...

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Detalles Bibliográficos
Autores principales: Jia, Fang, Fei, Si-Fan, Tong, De-Bing, Xue, Cong, Li, Jian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490038/
https://www.ncbi.nlm.nih.gov/pubmed/36160427
http://dx.doi.org/10.3389/fphar.2022.953845