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Determinants of affinity, specificity, and phase separation in a supramodule from Post-synaptic density protein 95
The post-synaptic density (PSD) is a phase-separated membraneless compartment of proteins including PSD-95 that undergoes morphological alteration in response to synaptic activity. Here, we investigated the interactome of a three-domain supramodule, PDZ3-SH3-GK (PSG) from PSD-95 using bioinformatics...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490041/ https://www.ncbi.nlm.nih.gov/pubmed/36157580 http://dx.doi.org/10.1016/j.isci.2022.105069 |