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Determinants of affinity, specificity, and phase separation in a supramodule from Post-synaptic density protein 95

The post-synaptic density (PSD) is a phase-separated membraneless compartment of proteins including PSD-95 that undergoes morphological alteration in response to synaptic activity. Here, we investigated the interactome of a three-domain supramodule, PDZ3-SH3-GK (PSG) from PSD-95 using bioinformatics...

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Detalles Bibliográficos
Autores principales: Laursen, Louise, Inturi, Raviteja, Østergaard, Søren, Jemth, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490041/
https://www.ncbi.nlm.nih.gov/pubmed/36157580
http://dx.doi.org/10.1016/j.isci.2022.105069

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