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Impaired Cdc20 signaling promotes senescence in normal cells and apoptosis in non–small cell lung cancer cells
Cellular senescence is a form of irreversible growth arrest that cancer cells evade. The cell division cycle protein 20 homolog (Cdc20) is a positive regulator of cell division, but how its dysregulation may relate to senescence is unclear. Here, we find that Cdc20 mRNA and protein expression are do...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490043/ https://www.ncbi.nlm.nih.gov/pubmed/35988650 http://dx.doi.org/10.1016/j.jbc.2022.102405 |