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Sphingosine 1 phosphate promotes hypertension specific memory T cell trafficking in response to repeated hypertensive challenges

We have previously shown that effector memory (TEM) cells accumulate in the bone marrow (BM) and the kidney in response to l-NAME/high salt challenge. It is not well understood if measures to block the exodus of that effector memory cells prevent redistribution of these cells and protect from hypert...

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Detalles Bibliográficos
Autores principales: Itani, Maha M., Jarrah, Hala, Maaliki, Dina, Radwan, Zeina, Farhat, Rima, Itani, Hana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490048/
https://www.ncbi.nlm.nih.gov/pubmed/36160839
http://dx.doi.org/10.3389/fphys.2022.930487