The E3 ubiquitin-protein ligase Nedd4-2 regulates the sodium chloride cotransporter NCC but is not required for a potassium-induced reduction of NCC expression

Na(+) and K(+) balance is influenced by the activity of the sodium chloride cotransporter NCC in the distal convoluted tubule. NCC activity and abundance are reduced by high extracellular K(+). The E3 ubiquitin ligase neural precursor cell expressed developmentally downregulated 4–2 (Nedd4-2) has be...

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Detalles Bibliográficos
Autores principales: Rosenbaek, Lena L., Petrillo, Federica, van Bemmelen, Miguel X., Staub, Olivier, Murali, Sathish K., Fenton, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490057/
https://www.ncbi.nlm.nih.gov/pubmed/36160843
http://dx.doi.org/10.3389/fphys.2022.971251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490057/
https://www.ncbi.nlm.nih.gov/pubmed/36160843
http://dx.doi.org/10.3389/fphys.2022.971251

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