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Optimal dose of cefotaxime in neonates with early-onset sepsis: A developmental pharmacokinetic model-based evaluation

Objective: The perspective of real-world study is especially relevant to newborns, enabling dosage regimen optimization and regulatory approval of medications for use in newborns. The aim of the present study was to conduct a pharmacokinetic analysis of cefotaxime and evaluate the dosage used in new...

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Detalles Bibliográficos
Autores principales: Shang, Zhen-Hai, Wu, Yue-E, Lv, Dong-Mei, Zhang, Wei, Liu, Wen-Qiang, van den Anker, John, Xu, Yan, Zhao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490083/
https://www.ncbi.nlm.nih.gov/pubmed/36160425
http://dx.doi.org/10.3389/fphar.2022.916253