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USP25 Deficiency Exacerbates Acute Pancreatitis via Up-Regulating TBK1–NF-κB Signaling in Macrophages

BACKGROUND & AIMS: Severe acute pancreatitis can easily lead to systemic inflammatory response syndrome and death. Macrophages are known to be involved in the pathophysiology of acute pancreatitis (AP), and macrophage activation correlates with disease severity. In this study, we examined the ro...

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Detalles Bibliográficos
Autores principales: Liu, Xin, Luo, Wu, Chen, Jiahao, Hu, Chenghong, Mutsinze, Rumbidzai N., Wang, Xu, Zhang, Yanmei, Huang, Lijiang, Zuo, Wei, Liang, Guang, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490099/
https://www.ncbi.nlm.nih.gov/pubmed/35934222
http://dx.doi.org/10.1016/j.jcmgh.2022.07.013