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In Vivo Genome-Wide CRISPR Activation Screening Identifies Functionally Important Long Noncoding RNAs in Hepatocellular Carcinoma

BACKGROUND & AIMS: Long noncoding RNAs (lncRNAs) are found to have profound impacts on diverse cellular processes. Although high-throughput sequencing studies have shown the differential lncRNA expression profiles between hepatocellular carcinoma (HCC) and nontumor livers, the functional impacts...

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Detalles Bibliográficos
Autores principales: Wong, Lok-Sze, Wei, Lai, Wang, Gengchao, Law, Cheuk-Ting, Tsang, Felice Ho-Ching, Chin, Wai-Ching, Ng, Irene Oi-Lin, Wong, Chun-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490101/
https://www.ncbi.nlm.nih.gov/pubmed/35944892
http://dx.doi.org/10.1016/j.jcmgh.2022.07.017