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Network pharmacology-based investigation and experimental validation of the mechanism of scutellarin in the treatment of acute myeloid leukemia

Background: It has been demonstrated that scutellarin, a natural flavone compound from Scutellaria lateriflora and Scutellaria barbata, exerts selective cytotoxicity against a range of cancer cells. However, the underlining mechanism of scutellarin on acute myeloid leukemia (AML) remains elusive. Me...

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Detalles Bibliográficos
Autores principales: Huang, Zhe, Yang, Yan, Fan, Xianming, Ma, Wenzhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9490111/
https://www.ncbi.nlm.nih.gov/pubmed/36160389
http://dx.doi.org/10.3389/fphar.2022.952677